Table 1. Demographics of patients with optic nerve disease (hereditary optic neuropathy HON and glaucoma GL) and their controls.
| Group | Sex | Age (yrs) | WT | HO | PSQI | BDI | Pupil (mm) | MD | RNFL | VA |
|---|---|---|---|---|---|---|---|---|---|---|
| HON Patients | 4F 7M | 39.4# (15.2) | 6:49 (0:56) | 58.1 (5.7) | 4.4* (2.0) | 1.7 (1.8) | 4.88 (1.65) | 7.3* (5.4) | 63.9* 10.5) | 0.4*,# (0.3) |
| GL Patients | 8F 3M | 54.1 (7.1) | 6:11 (1:15) | 62.0 (8.3) | 5.5* (3.8) | 2.2 (2.0) | 4.61 (1.01) | 11.4* (6.2) | 59.8* (16.5) | 0.7* (0.2) |
| HON Controls | 8F 3M | 36.2§ (13.2) | 7:17 (0:40) | 58.6 (9.6) | 2.4 (1.9) | 0.9 (1.0) | 5.15 (1.28) | −0.7 (0.9) | 104.5 (7.9) | 1.1 (0.1) |
| GL Controls | 7F 4M | 54.4 (7.2) | 7:02 (0:41) | 59.4 (7.1) | 2.8 (1.5) | 1.6 (1.5) | 4.99 (0.79) | –0.6 (0.8) | 96.5 (13.1) | 1.0 (0.1) |
Demographics for GL and HON Patients (Pat) and Controls of both groups; mean (± SD); N = 11 in each group. WT=habitual wake time (clock time); HO = Horne Ostberg; PSQI = Pittsburgh Sleep Quality Index; BDI = Beck Depression Inventory; MD = Mean Deviation of automated perimetry; RNFL = mean peripapillary retinal nerve fiber layer thickness (μm); VA = Visual Acuity.
*significant differences (p < 0.05) between patients and their controls (separately for GL and HON).
#significant difference between both patient groups (p < 0.05).
§significant difference between both control groups (p < 0.05). Absolute pupil sizes are indicated as mean values for all tests per participants and all ophthalmological values (pupil size, MD, RNFL, VA) were averaged for left and right eyes.