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. 2015 Oct 19;5:15145. doi: 10.1038/srep15145

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(a) Overlap enrichment between up-regulated aging genes and disease genes in GTEx tissues and (b) Overlap enrichment between down-regulated aging genes and disease genes in GTEx tissues. The color depth indicates the normalized negative logarithm of the p-value of the Fisher’s exact test for overlapping between disease and aging genes in specific tissue.

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