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. Author manuscript; available in PMC: 2016 Aug 21.
Published in final edited form as: Nanomedicine (Lond). 2015 Aug 21;10(16):2481–2497. doi: 10.2217/NNM.15.90

Figure 5. Blood and urinary clearance of 3H-multiwalled carbon nanotube-DSPE-PEG-glucosamine.

Figure 5

MDA-MB-231 were established as xenografts in nude mice. Nude mice (n = 3–8 per group) were injected intravenously with free 3H-DSPE-PEG-GlcN, 3H-GlcN (0.1 μCi [low dose] or 1.3 μCi [high dose]), 3H-MWCNT-DSPE-PEG-GlcN (0.1 μCi [low dose] or 1.3 μCi [high dose] or PBS control and placed in metabolic cages. (A) Blood samples were obtained 10 min, 60 min and 24 h postinjection, and radioactivity was quantified by scintillation counting. Data are shown as percentage injected dose per ml blood ± standard error. (B) Pooled urine was collected at 0–1 h and (C) 1–24 h after injection, and radioactivity was quantified by scintillation counting. Data in (B) are shown as percentage injected dose per ml urine.

GlcN: Glucosamine; MWCNT: Multiwalled carbon nanotube.