Table 1.
Dose–response data for chromosome aberrations per 100 cells induced by 5 different energies of protons measured in first post irradiation chemically induced PCC.
| Dose (Gy) | Cells scored | Simple exchanges | Complex exchanges |
|---|---|---|---|
| E = 5 MeV | |||
| 0.10 | 1018 | 2.3 ± 0.7 | 0 ± 0 |
| 0.20 | 1044 | 1.2 ± 0.9 | 0.7 ± 0.4 |
| 0.40 | 909 | 6.8 ± 1.6 | 1.1 ± 0.6 |
| 0.70 | 869 | 8.0 ± 1.7 | 2.1 ± 0.8 |
| 1.00 | 634 | 14.9 ± 2.6 | 4.3 ± 1.3 |
| E = 120 MeVa | |||
| 0.15 | 1188 | 1.5 ± 0.6 | 0.4 ± 0.3 |
| 0.30 | 1437 | 2.1 ± 0.6 | 1.0 ± 0.4 |
| 0.50 | 1369 | 3.6 ± 0.8 | 2.7 ± 0.7 |
| 0.75 | 1136 | 6.1 ± 1.2 | 2.4 ± 0.7 |
| 1.00 | 825 | 13.8 ± 2.0 | 3.6 ± 1.0 |
| 1.50 | 357 | 31.2 ± 4.7 | 11.1 ± 2.8 |
| 2.00 | 203 | 61.0 ± 8.6 | 34.2 ± 6.5 |
| E = 250 MeV | |||
| 0.25 | 491 | 1.9 ± 1.8 | 3.1 ± 1.3 |
| 0.50 | 536 | 2.8 ± 1.8 | 5.3 ± 1.6 |
| 0.80 | 427 | 5.2 ± 2.3 | 3.6 ± 1.5 |
| 1.20 | 563 | 7.6 ± 2.3 | 5.5 ± 1.6 |
| 2.00 | 325 | 29.4 ± 5.1 | 11.1 ± 3.0 |
| E = 800 MeV | |||
| 0.25 | 330 | 0 ± 1.1 | 2.3 ± 1.4 |
| 0.50 | 609 | 0 ± 0.8 | 0.4 ± 0.4 |
| 0.80 | 655 | 13.8 ± 2.6 | 5.1 ± 1.4 |
| 1.20 | 561 | 14.0 ± 2.9 | 6.0 ± 1.7 |
| 2.00 | 263 | 35.2 ± 6.2 | 7.8 ± 2.8 |
| E = 1000 MeV | |||
| 0.20 | 231 | 3.0 ± 2.2 | 0 ± 0 |
| 1.20 | 321 | 13.0 ± 3.7 | 4.3 ± 2.2 |
| 3.00 | 134 | 87.9 ± 15.1 | 38.8 ± 10.0 |
| E = 2000 MeV | |||
| 0.25 | 330 | 0.7 ± 1.3 | 0.8 ± 0.8 |
| 0.50 | 284 | 9.7 ± 3.2 | 6.1 ± 2.3 |
| 0.80 | 378 | 13.5 ± 3.1 | 3.3 ± 1.5 |
| 1.20 | 538 | 9.9 ± 2.3 | 7.4 ± 1.8 |
| 2.00 | 243 | 46.3 ± 7.0 | 15.3 ± 4.0 |
| E = 2500 MeV | |||
| 0.20 | 1342 | 1.4 ± 0.5 | 0.8 ± 0.4 |
| 0.40 | 1127 | 3.4 ± 0.9 | 2.1 ± 0.7 |
| 0.60 | 1635 | 7.6 ± 1.1 | 2.6 ± 0.6 |
| 0.80 | 218 | 7.1 ± 2.9 | 4.7 ± 2.4 |
| 1.20 | 304 | 24.7 ± 4.6 | 4.3 ± 1.9 |
Data represent whole-genome equivalent values with background subtracted. a150 MeV protons with 5 cm polyethylene shielding leading to residual energy of 120 MeV.