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. 2015 Sep 14;4(10):1281–1289. doi: 10.1242/bio.013623

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© 2015. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 3. — Mathematical model results showing the time course of HIF1α accumulation at oxygen levels ranging from 0.01% to 21% oxygen, as indicated. (A) Control SDHB knockdown HEK293 cells. (B) Control Sdhc knockout fibroblasts.