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. 2015 Oct 1;8(10):1237–1246. doi: 10.1242/dmm.021071

Fig. 3.

Fig. 3.

C4PY is a ligand of GPER. (A) C4PY competes with [3H]E2 for binding to GPER in SkBr3 cells. Competition curves of increasing concentration of unlabeled E2, G-1 and C4PY expressed as a percentage of maximum specific [3H]E2 binding. Each data point represents the mean±s.d. of triplicate samples of three separate experiments. (B) C4PY competes with [5,6-3H] nicotinic acid (NA) for binding to GPER in SkBr3 cells. Competition curves of increasing concentration of unlabeled NA, G-1 and C4PY expressed as a percentage of maximum specific [5,6-3H] NA binding. Each data point represents the mean±s.d. of three separate experiments performed in triplicate.