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. 2015 Oct 1;8(10):1323–1337. doi: 10.1242/dmm.021436

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© 2015. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — Functional effects of chronic ototoxic exposure and washout. (A,B) Rats were administered 0 (control), 10 or 20 mM IDPN in their drinking water for 4 (A) or 10 (B) weeks. Data are ratings for vestibular dysfunction from a battery of behavioral tests. The animals were assessed weekly during exposure and at one- or two-week intervals during a washout period of similar length. The higher number of animals per group corresponds to the total number of animals during the exposure period; the lower number to the animals remaining in the washout period. *P<0.05.