. Author manuscript; available in PMC: 2016 Nov 1.

Published in final edited form as: J Neuropathol Exp Neurol. 2015 Nov;74(11):1086–1092. doi: 10.1097/NEN.0000000000000254

Table 3.

Mean Test Score at First Assessment: Adjustment Method 1

Test by domain	Non-progressors		Progressors		Estimate (95% CI)^b	P-value^c
Test by domain	n	Mean (SD)^a	n	Mean (SD)^a	Estimate (95% CI)^b	P-value^c
Episodic memory	128	0.18 (0.95)	152	−0.30 (0.98)	−0.34 (−0.50, −0.18)	.0001
Attention	130	−0.12 (0.85)	152	−0.17 (0.84)	−0.03(−0.23,0.18)	.80
Executive function	131	−0.38 (0.89)	141	−1.01 (1.25)	−0.58 (−0.83, −0.32)	<.0001
Language	129	−0.12 (0.61)	149	−0.55 (0.72)	−0.38 (−0.54, −0.22)	<.0001
Global composite	121	−0.10 (0.52)	130	−0.49 (0.60)	−0.33 (−0.46, −0.19)	<.0001

The mean scores and standard deviations presented are raw values, not estimated from the model.

The term “estimate” indicates the difference in means cores between progressors and non-progressors, adjusted for the variables in the model.

p values were determined from generalized estimating equations model predicting test score by AD-NP status adjusting for age at visit (continuous), education (categorical), and sex (categorical).

AD-NP, Alzheimer disease neuropathologic change; CI, confidence interval.