Table 4.
Mean Test Score at First Assessment: Adjustment Method 2
| Test by domain | Non-progressors | Progressors | Estimate (se)b | p valuec | ||
|---|---|---|---|---|---|---|
| n | Mean (SD)a | n | Mean (SD)a | |||
| Episodic memory | 108 | 0.13 (0.91) | 133 | −0.33 (0.97) | −0.44 (−0.68, −0.19) | .0006 |
| Attention | 109 | −0.13 (0.82) | 133 | −0.18 (0.86) | −0.01(−0.24,0.21) | .91 |
| Executive function | 108 | −0.38 (0.93) | 120 | −1.01 (1.29) | −0.60 (−0. 94, −0.26) | .0006 |
| Language | 109 | −0.11 (0.61) | 130 | −0.56 (0.74) | −0.43 (−0.61, −0.24) | <.0001 |
| Global composite | 104 | −0.11 (0.50) | 114 | −0.50 (0.61) | −0.34 (−0.50, −0.18) | <.0001 |
a
The mean scores and standard deviations presented are raw values, not estimated from the model.
b
The term “estimate” indicates the difference in means cores between progressors and non-progressors, adjusted for the variables in the model.
c
P-values were determined from generalized estimating equations model predicting test score by Alzheimer disease neuropathologic change status adjusting for age at visit, education, sex, presence of infarcts or lacunes, presence of hemorrhages or microbleeds, and presence of cerebral amyloid angiopathy.