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. Author manuscript; available in PMC: 2015 Oct 19.
Published in final edited form as: JAMA Pediatr. 2013 Oct;167(10):947–953. doi: 10.1001/jamapediatrics.2013.2259

Table 5.

Autism Spectrum Disorders (ASDs) Relative Recurrence Risk in the Maternal and Paternal Sibling Subcohorts

Variable Crude Relative Recurrence Risk
(95% CI)		 P Valueb P Valuec Adjusted Relative Recurrence Risk
(95% CI)a 		P Valueb P Valuec
Maternal Sibling Subcohort
All 6.5 (5.5–7.7) <.001 6.3 (5.3–7.4) <.001
Full-siblings 7.5 (6.2–8.9) <.001 <.001 7.5 (6.3–9.0) <.001 <.001
Half-siblings 2.4 (1.4–4.2) .002 2.4 (1.4–4.1) .002
Paternal Sibling Subcohort
All 6.4 (5.4–7.6) <.001 6.3 (5.3–7.5) <.001
Full-siblings 7.5 (6.3–9.0) <.001 <.001 7.4 (6.2–8.9) <.001 <.001
Half-siblings 1.4 (0.6–3.2) .37 1.5 (0.7–3.4) .32
a

Parental psychiatric history defined as at least 1 psychiatric diagnosis before the birth of the child.

b

Test for no relative recurrence risk.

c

Test for no difference in the relative recurrence risk for full-siblings and half-siblings.