Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Adverse effects
RCT	50 people with paracetamol (acetaminophen) poisoning	Proportion of people with no sign or symptom of anaphylactoid reaction (not specifically defined but may have included nausea and vomiting, dyspnoea, flushing, and headache) 39% with IV acetylcysteine 87% with oral plus IV acetylcysteine Absolute numbers not reported	P = 0.004 Result should be interpreted with caution (see Further information on studies)	Effect size not calculated	oral plus IV acetylcysteine