Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Live birth rates
Systematic review	Women with unexplained recurrent miscarriage 8 RCTs in this analysis	Proportion of women having a live birth 92/159 (58%) with intravenous immunoglobulin 85/144 (59%) with placebo	OR 0.98 95% CI 0.61 to 1.58 P = 0.94 This analysis was not ITT A sensitivity analysis of RCTs reporting an ITT analysis also found no significant difference between groups (4 RCTs, 279 women, OR 1.18, 95% CI 0.72 to 1.93) See Further information on studies		Not significant
Systematic review	Women with unexplained recurrent miscarriage 6 RCTs in this analysis	Live birth rate per participant randomised 88/139 (63%) with intravenous immunoglobulin 87/133 (65%) with placebo	OR 0.92 95% CI 0.55 to 1.54 P = 0.30 The review also performed a sub-group analysis by type of miscarriage and treatment start time (see Further information on studies)		Not significant