Figure 5.

There is no correlation between expression of systemic lupus erythematosus (SLE) associated CD229 Met₆₀₂ and increased activation of healthy primary human cells. (a) CD229 and (b) CD3 expression on primary peripheral blood mononuclear cells (PBMCs) from five healthy donors (values represent means of expression levels measured directly after PBMC isolation and before CD3 stimulation). (c) Percentage of CD69⁺ primary T lymphocytes after anti‐CD3ε stimulation of PBMCs. T cells were gated as T‐cell receptor αβ+. Data represent triplicates of one experiment.