Table 3.
Postdiagnostic TV watching, colorectal cancer-specific mortality, mortality from other causes and overall mortality
| Postdiagnostic sitting watching TV, h/wk |
Ptrend | per 14-h/wk increment |
≥21 vs <21 | ||||
|---|---|---|---|---|---|---|---|
| 0–6 | 7–13 | 14–20 | ≥21 | ||||
| Colorectal cancer-specific mortality | |||||||
| No. of deaths (n=72) | 34 | 8 | 11 | 19 | |||
| Age-adjusted | 1.00(ref) | 0.61(0.28–1.32) | 0.78(0.40–1.55) | 1.80(1.03–3.16) | 0.11 | 1.28(0.95–1.73) | 2.08(1.23–3.52) |
| Multivariable* with physical activity† | 1.00(ref) | 0.63(0.28–1.38) | 0.75(0.36–1.56) | 1.42(0.80–2.52) | 0.26 | 1.20(0.87–1.64) | 1.63(0.96–2.79) |
| Further adjusted for BMI, change in BMI‡ and AHEI§ | 1.00(ref) | 0.60(0.27–1.35) | 0.67(0.32–1.44) | 1.53(0.84–2.77) | 0.20 | 1.24(0.89–1.71) | 1.81(1.03–3.16) |
| Further adjusted for prediagnosistic TV watching | 1.00(ref) | 0.62(0.27–1.41) | 0.68(0.30–1.54) | 1.45(0.73–2.87) | 0.27 | 1.23(0.86–1.76) | 1.79(0.97–3.28) |
| Mortality from other causes | |||||||
| No. of deaths (n=253) | 122 | 45 | 51 | 35 | |||
| Age-adjusted | 1.00(ref) | 1.06(0.75–1.50) | 1.11(0.80–1.54) | 0.98(0.67–1.43) | 0.96 | 1.00(0.84–1.20) | 0.95(0.66–1.35) |
| Multivariable* with physical activity† | 1.00(ref) | 1.10(0.77–1.57) | 1.15(0.82–1.62) | 0.98(0.66–1.43) | 0.90 | 0.99(0.83–1.18) | 0.93(0.64–1.34) |
| Further adjusted for BMI, change in BMI‡ and AHEI§ | 1.00(ref) | 1.07(0.74–1.55) | 1.08(0.76–1.54) | 0.98(0.67–1.45) | 0.81 | 0.98(0.81–1.17) | 0.96(0.66–1.39) |
| Further adjusted for prediagnosistic TV watching | 1.00(ref) | 1.08(0.74–1.57) | 1.09(0.75–1.59) | 1.03(0.66–1.60) | 0.94 | 0.99(0.80–1.23) | 0.98(0.65–1.49) |
| Overall mortality | |||||||
| No. of deaths (n=325) | 156 | 53 | 62 | 54 | |||
| Age-adjusted | 1.00(ref) | 0.95(0.69–1.30) | 1.03(0.77–1.38) | 1.17(0.85–1.59) | 0.43 | 1.06(0.91–1.24) | 1.17(0.87–1.57) |
| Multivariable* with physical activity† | 1.00(ref) | 1.00(0.72–1.38) | 1.06(0.78–1.44) | 1.11(0.81–1.52) | 0.67 | 1.03(0.89–1.21) | 1.10(0.81–1.48) |
| Further adjusted for BMI, change in BMI‡ and AHEI§ | 1.00(ref) | 0.96(0.69–1.34) | 0.98(0.72–1.35) | 1.12(0.81–1.54) | 0.74 | 1.03(0.88–1.20) | 1.13(0.83–1.53) |
| Further adjusted for prediagnosistic TV watching | 1.00(ref) | 0.98(0.70–1.37) | 1.01(0.72–1.42) | 1.16(0.80–1.68) | 0.66 | 1.04(0.87–1.25) | 1.16(0.83–1.63) |
*
Adjusted for age at diagnosis, years of diagnosis, stage of disease, grade of differentiation, tumor location, and postdiagnostic smoking status; results were similar if additionally adjusted for regular aspirin use, alcohol, folate, calcium, red meat, and energy intake.
†
Postdiagnostic physical activity.
‡
Postdiagnostic BMI and change in BMI (postdiagnostic BMI-prediagnostic BMI; <-2, −2- <2, ≥2 kg/m2).
§
Postdiagnostic AHEI 2010 and energy intake.