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. 2015 Oct 14;8:2923–2931. doi: 10.2147/OTT.S91460

Figure 1.

Figure 1

Immunohistochemical staining of SFRP1 in normal oral mucosa, OSF, and OSCC tissues.

Notes: Normal oral tissues exhibited strongly positive SFRP1 protein expression in the nucleus. OSF early stage and moderately advanced stage tissues showed SFRP1-positive expression in the cytoplasm and nucleus. OSF advanced stage tissues showed weak SFRP1 expression in cytoplasmic parts. Primary OSCC showed very weak cytoplasmic immunoreaction for SFRP1. Original magnification was ×400.

Abbreviations: SFRP, secreted frizzled-related protein; OSF, oral submucous fibrosis; OSCC, oral squamous cell carcinoma.