Table S4.
Residue | Δδ/ΔT (ppb/K) |
---|---|
1 C | – |
2 P | – |
3 I | −10.0±0.4 |
4 F | −1.5±0.3 |
5 T | −0.6±0.3 |
6 K | −1.1±0.5 |
7 I | −4.7±0.7 |
8 Q | −5.8±0.6 |
9 G | −3.3±0.8 |
10 T | −5.0±0.5 |
11 C | −2.6±0.5 |
12 G | −6.5±0.3 |
13 G | −5.3±0.4 |
14 R | – |
15 R | −4.5±0.8 |
16 K | −6.7±0.6 |
17 K | −5.6±0.6 |
Notes: Δδ/ΔT for Arg14 could not be determined due to chemical shift overlaps at higher temperatures. Data are presented as mean ± standard deviation.
Abbreviations: AMC, antimicrobial cyclic peptide; TFE, 2-2-2 trifluoroethanol-d3; C, cysteine; P, proline; I, isoleucine; F, phenylalanine; T, threonine; K, lysine; Q, glutamine; G, glycine; R, arginine.