Table 4.
Factors associated with hepatitis B reactivation, multivariate cox proportional hazard model — Alaska, 2001–2010.
| Variable | Adjusted Hazard Ratio (95%CI) | P-Value |
|---|---|---|
| Age at study entry (years) | ||
| 18–29 | 1.00 | |
| 30–39 | 0.34 (0.12, 0.90) | 0.03 |
| 40–49 | 0.20 (0.05, 0.70) | 0.01 |
| 50+ | 0.77 (0.33, 1.77) | 0.53 |
| Sex | ||
| Females | 1.00 | |
| Males | 2.41 (1.17, 4.96) | 0.01 |
| HBV DNA levels at study entry (IU/mL) | ||
| <29 | 1.00 | |
| 29–199 | 2.51 (0.75, 8.36) | 0.13 |
| 200–999 | 2.28 (0.80, 6.46) | 0.12 |
| 1000–1999 | 7.61 (2.81, 20.6) | <0.001 |
| HBV genotype | ||
| Non-B | 1.00 | |
| B | 6.08 (1.32, 28.0) | 0.02 |
HR, Hazard Ratio; CI, confidence interval; HBV, hepatitis B virus