Table 1.
Level of antibody to hepatitis B surface antigen (anti-HBs) after 3 doses of hepatitis B vaccine among older adults by demographic and clinical characteristics—Houston, 2010.
| Characteristic | Total sample N (%) | Anti-HBs < 10 mIU/ml N (%) | Anti-HBs ≥ 10 mIU/ml N (%) | p-Value | Anti-HB4s GMC
|
|
|---|---|---|---|---|---|---|
| GMC | 95%CI | |||||
| Total | 48 | 32 (66.7%) | 16 (33.3%) | – | 4.8 | 2.58–8.91 |
| Age (years) | ||||||
| ≤60 | 8 (16.7%) | 1 (12.5%) | 7 (87.5%) | 0.001 | 72.7 | 11.35–466.00 |
| 61–69 | 0 (0.0%) | – | – | – | – | |
| 70–79 | 3 (6.2%) | 2 (66.7%) | 1 (33.3%) | 9.8 | 0.0–124012.6 | |
| 80–89 | 20 (41.7%) | 14 (70.0%) | 6 (30.0%) | 3.7 | 1.67–8.28 | |
| ≥90 | 17 (35.4%) | 15 (88.2%) | 2 (11.7%) | 1.6 | 1.02–2.46 | |
| Sex | ||||||
| Male | 7 (14.6%) | 6 (85.7%) | 1 (14.3%) | 1.0 | 3.0 | 0.30–29.83 |
| Female | 25 (52.1%) | 19 (76.0%) | 6 (24.0%) | 3.0 | 1.60–5.83 | |
| Missing | 16 (33.3%) | 7 (43.7%) | 9 (56.3%) | |||
| Race | ||||||
| White | 32 (66.7%) | 25 (78.1%) | 7 (21.9%) | N/A | 3.0 | 1.61–5.73 |
| Missing | 16 (33.3%) | 7 (43.7%) | 9 (56.3%) | |||
| Ethnicity | ||||||
| Non-Hispanic | 23 (47.9%) | 18 (78.3%) | 5 (21.7%) | N/A | 3.6 | 1.57–8.10 |
| Missing | 25 (52.1%) | 14 (56.0%) | 11 (44.0%) | |||
| Diabetes | ||||||
| No | 42 (87.5%) | 27 (64.3%) | 15 (35.7%) | 0.6 | 5.1 | 2.69–9.74 |
| Yes N (%) | 5 (10.4%) | 4 (80.0%) | 1 (20.0%) | 3.8 | 0.09–154.51 | |
| Missing | 1 (2.1%) | 1 (100.0%) | 0 (0.0%) | |||
| BMI | ||||||
| Normal (18.5 to <25) | 11 (22.9%) | 10 (90.9%) | 1 (9.1%) | 0.5 | 2.1 | 0.78–5.64 |
| Overweight (25–29) | 13 (27.1%) | 9 (69.2%) | 4 (30.8%) | 3.1 | 1.18–7.95 | |
| Obese (≥30) | 5 (10.4%) | 4 (80.0%) | 1 (20.0%) | 6.5 | 0.19–219.76 | |
| Missing | 19 (39.6%) | 9 (47.4%) | 10 (52.6%) | |||
| Smoking | ||||||
| Non-smoker | 29 (60.4%) | 23 (79.3%) | 6 (20.7%) | 0.4 | 2.6 | 1.48–4.63 |
| Smoker (ex and current) | 2 (4.2%) | 1 (50.0%) | 1 (50.0%) | 28.1 | 0.00–7.27 × 1019 | |
| Missing | 17 (35.4%) | 8 (47.1%) | 9 (52.9%) | |||
| Alcohol | ||||||
| No | 9 (18.7%) | 7 (77.8%) | 2 (22.2%) | 1.0 | 5.4 | 0.84–34.57 |
| Yes | 12 (25.0%) | 9 (75.0%) | 3 (25.0%) | 2.7 | 0.98–7.31 | |
| Missing | 27 (56.3%) | 16 (59.2%) | 11 (40.7%) | |||
| History of cancer | ||||||
| No | 30 (62.5%) | 24 (80.0%) | 6 (20.0%) | 0.5 | 2.9 | 1.52–5.65 |
| Yes | 3 (6.3%) | 2 (66.7%) | 1 (33.3%) | 3.0 | 0.03–352.27 | |
| Missing | 15 (31.2%) | 6 (40.0%) | 9 (60.0%) | |||
| Moderate renal disease | ||||||
| No | 27 (56.3%) | 21 (77.8%) | 6 (22.2%) | 1.0 | 3.0 | 1.52–6.07 |
| Yes | 6 (12.5%) | 5 (83.3%) | 1 (16.7%) | 2.5 | 0.37–17.68 | |
| Missing | 15 (31.2%) | 6 (40.0%) | 9 (60.0%) | |||