Figure 1.
Allelic imbalance in nine ESCC sample pairs detected using exome sequencing
Bar plots illustrating the minor allele fraction (MAF) of informative SNPs in each exome of blood and tumor samples. The X-axis indicates the genomic position of each informative SNP on autosomes. The imbalanced regions revealed by window-sliding method are indicated in red. Apparently tumor samples from patients 99648, 100036, and 102995 were rarely affected by any alteration characterized by allelic imbalance as seen in the other six tumor samples.