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. 2015 Oct 20;9:267. doi: 10.3389/fnbeh.2015.00267

Figure 2.

Figure 2

Effect of long-term POL60 treatment on working memory in Ts65Dn mice: Per cent of alternation was assessed in four groups of mice: WT and Ts administered placebo, n = 12; and WT and Ts with POL60 treatment, n = 8. The data have been normalized to the baseline level of performance of wild-type mice fed with water (dotted line). Ts65Dn mice displayed a very significant decrease of alternation under placebo condition. POL60 treatment produced improved alternation performance in the Ts65Dn mice. ***p < 0.001, **p < 0.01.