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. 2015 Oct 20;9:267. doi: 10.3389/fnbeh.2015.00267

Figure 3.

Figure 3

Cognitive performance of GTE (or MGTE)-treated mBACtgDyrk1a in the Y maze. The effects of Dyrk1A overexpression on short-term spatial memory were assessed in a spontaneous alternation paradigm in a Y–maze. The data have been normalized to the baseline level of performance of wild-type mice fed with water (dotted line). One mouse from the BACtgDyrk1a group was excluded from statistical analysis because of abnormally high levels of locomotor activity and associated erratic exploration, precluding assessment of memory scores. The rate of spontaneous alternation (visiting each arm in turn) was affected by genotype: mBACtgDyrk1a mice alternated less than wild-type mice (P < 0.05). Treatment with MGTE significantly improved performance of mBACtgDyrk1a mice. *p < 0.05.