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. 2015 Oct 20;9:384. doi: 10.3389/fnins.2015.00384

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Copyright © 2015 Nagarah, Stowasser, Parker, Asari and Wagenaar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of electrode-tissue interface. (A) Electrical equivalence model of electrode and solution with circuit elements: R_sol (solution resistance), Q_int (constant phase angle impedance representing the interface capacitance), R_ct (electrode charge transfer resistance). (B) Theoretical model of absolute value (red) and phase (blue, dashed) of electrode impedance as a function of frequency. (C) Actual measurements of absolute value (top) and phase (bottom) of electrode impedance, before a slice was placed on the array (black squares), with a slice present but before suction was applied (blue crosses), and with a slice with suction applied (red triangles).