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Streptococcal pyrogenic exotoxin A- induced surface molecules. CD14+ monocytes were stimulated with increasing concentrations of SPEA as indicated. 24 h after stimulation cells were harvested and analyzed for surface markers by flow cytometry (A) MHC-II, (B) CD80, (C) CD86 and (D) PD-L1. The mean fluorescent intensity of three different experiments is shown. The line represents the mean of the experiments.
