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. 2015 Oct 20;6:1153. doi: 10.3389/fmicb.2015.01153

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Copyright © 2015 Sähr, Förmer, Hildebrand and Heeg.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cyclosporine A – mediated expression of mRNA. CD14⁺ monocytes were stimulated 24 h with SPEA (100 ng/ml) and CsA (1 μM) or Ethanol (equal volume to CsA). Quantitative real-time PCR of cDNA was performed with sequence-specific primers for (A) CD274, (B) Il1b, (C) IDO, (D) TDO. Data were normalized to ß-Actin. Shown is the mean and standard deviation of 5 donors. Statistical analysis was performed using a Multiple Comparison of Means (Tukey Contrasts). Significance codes: 0 ‘^∗∗∗’; 0.001 ‘^∗∗’; 0.01 ‘^∗’.