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. 2015 Jul 15;115(5):460–470. doi: 10.1038/hdy.2015.53

Table 3. Coalescent simulations with and without selection.

  Recombination parameter
  C=0 C=Rm C=R
No selection
 (A) Number of data sets 10 000 10 000 10 000
   P (i⩾14) 0.120 0.064 0.013
 (B) Number of data sets 1200 643 126
   P (d<5∪d>30) 0.10 <0.01 <0.01
       
Selection coefficient, s=0.01
 (C) Number of data sets 1000 1000 1000
   P (i⩾14) >0.90 >0.90 >0.85
 (D) Number of data sets 976 974 954
   P (d<5∪d>30) 0.05 <0.01 <0.001
       
Selection coefficient, s=0.1
 (E) Number of data sets 1000 1000 1000
   P (i⩾14) >0.95 >0.95 >0.95
 (F) Number of data sets 977 968 962
   P (d<5∪d>30) 0.04 <0.01 <0.001

Probability of observing (A, C, E) a minimum of i identical sequences using a threshold value determined from empirical observations of the frequency of the Del200 haplogroup and (B, D, F) a major haplogroup that is highly divergent from all other alleles in the population whereby the pairwise distance, d, between the major allele and all other sequences in a data set is either <5 (representing variants within the Del200 haplogroup) or >30 (representing the 31 fixed differences between the Ins200 and Del200 haplogroups). All data sets were simulated using the parameters n=63 and S=80. For simulations with selection, Ne ranged from 105 to 107and the SF option with t=0 and f=0.3 was used (Ewing and Hermisson, 2010). In addition to a no recombination scenario, two estimates of the recombination parameter, C, were included: the minimum number of recombination events, Rm=5 (Hudson, 1987), and the estimator based on the variance of the average number of differences between pairs of sequences, R=21.7 (Hudson and Kaplan, 1985).