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. 2015 Oct 5;5(10):e008344. doi: 10.1136/bmjopen-2015-008344

Table 5.

Mean (95% CI) of salivary cortisol (nmol/L), STAI and CA during simulation in management of an emergency caesarean section and postpartum haemorrhage conducted as ISS and OSS

    Baseline Postsimulation
0 min
Mean*
Postsimulation
5 min
Mean*
Postsimulation
10 min
Mean*
Peak-level mean*† Mean difference*‡ of baseline to peak of ΔOSS versus ΔISS
First simulation: emergency caesarean section
 Cortisol ISS 7.0 (6.3 to 7.8) 8.9 (7.2 to 10.6) 8.1 (6.6 to 9.6) 8.1 (6.6 to 9.5) 9.3 (7.6 to 11.0) −0.5 (−1.6 to 2.5) p=0.64
OSS 7.3 (5.3 to 9.2) 8.2 (6.3 to 10.2) 7.8 (6.1 to 9.6) 8.0 (6.2 to 9.8) 9.0 (6.9 to 11.1)
 STAI ISS 32.2 (30.4 to 34.0) 34.8 (32.7 to 37.0) 31.3 (29.5 to 33.1) 36.5 (34.3 to 38.7) −0.2 (−2.1 to 2.5) p=0.85
OSS 33.1 (31.1 to 35.0) 34.8 (32.2 to 37.3) 30.7 (29.0 to 32.4) 37.0 (34.7 to 39.3)
 CA ISS 1.0 (0.9 to 1.1) 0.8 (0.7 to 1.0) 0.8 (0.7 to 0.9) 0.8 (0.7 to 1.0.) 0.0 (−0.2 to 0.2) p=0.93
OSS 1.0 (1.0 to 1.1) 0.8 (0.7 to 0.9) 0.8 (0.6 to 0.9) 0.9 (0.7 to 0.9)
Second simulation: postpartum haemorrhage
 Cortisol ISS 7.4 (6.5 to 8.3) 9.2 (7.7 to 10.7) 7.7 (6.6 to 8.8) 7.4 (6.3 to 8.5) 9.4 (7.9 to 10.9) −1.2 (−0.1 to 0.25) p=0.07
OSS 6.9 (5.9 to 7.9) 7.5 (6.6 to 8.4) 6.7 (5.8 to 7.7) 6.8 (6.0 to 7.6) 7.7 (6.7 to 8.7)
 STAI ISS 31.8 (30.0 to 33.6) 31.8 (30.1 to 33.6) 28.5 (27.3 to 29.7) 32.2 (30.5 to 33.9) −0.5 (−2.2 to 1.3) p=0.61
OSS 32.1 (29.9 to 34.2) 32.4 (30.5 to 34.3) 30.1 (28.5 to 31.8) 32.8 (31.0 to 34.7)
 CA ISS 1.0 (0.9 to 1.1) 0.8 (0.7 to 0.9) 0.8 (0.7 to 0.9) 0.8 (0.7 to 0.9) 0.1 (−0.2 to 0.1) p=0.56
OSS 1.1 (1.0 to 1.2) 0.9 (0.7 to 1.0) 0.8 (0.7 to 0.9) 0.9 (0.7 to 1.0)

*Based on generalised estimating equations to account for potential correlation within teams.

†Peak level is the maximum of the measurements obtained at 0, 5 and 10 min after the end of the simulation.

‡Adjusted for pre-cortisol, pre-STAI and pre-CA (ANCOVA).

ANCOVA, analysis of covariance;CA, cognitive appraisal (range 0.1–10); ISS, in situ simulation; OSS, off-site simulation; STAI, Stress-Trait Anxiety Inventory (range 20–80).