Table 1.
Dynamic alteration of RCC, RT and Kd in cirrhotic liver tissues
Time |
RCC (%) |
RT (fmol/mg protein) |
Kd (nM) |
|||
Control Group | Model Group | Control Group | Model Group | Control Group | Model Group | |
3rd week | 1.29 ± 0.23 | 1.56 ± 0.35 | 75.8 ± 5.1 | 55.2 ± 4.5b | 0.62 ± 0.03 | 0.61 ± 0.07 |
6th week | 1.19 ± 0.21 | 10.8 ± 2.5ab | 77.3 ± 4.3 | 42.6 ± 2.1ab | 0.64 ± 0.05 | 0.58 ± 0.06 |
9th week | 1.16 ± 0.18 | 20.2 ± 3.6ab | 74.9 ± 3.9 | 30.8 ± 1.9ab | 0.61 ± 0.09 | 0.60 ± 0.04 |
12th week | 1.27 ± 0.25 | 28.0 ± 4.3ab | 73.2 ± 5.4 | 17.5 ± 2.5ab | 0.60 ± 0.08 | 0.59 ± 0.07 |
15th week | 1.13 ± 0.24 | 15.2 ± 2.6ab | 71.5 ± 4.9 | 20.8 ± 1.6b | 0.58 ± 0.06 | 0.61 ± 0.09 |
P < 0.05 vs a previous time point,
P < 0.05 vs control group. RCC: Relative content of collagen (%) indicating severity of liver fibrosis; RT: Total binding capacity of receptors (fmol/mg protein) corre-sponding to the quantity of receptors; Kd: Dissociation constant in equilibrium (nM) which is equal to the affinity of receptors.