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Circulation IL-6, TNF-α levels during hyperglyce-mia clamps in 20 patients of control group (○-○) and in 20 patients of IGT group (△-△). Mean ± S.E.M. in human sepsis. In two groups, plasma IL-6, TNF-α levels rose from a basal value to a peak within 1 hour (P < 0.01). In IGT group, increased level of plasma TNF-α, IL-6 during the clamping lasted longer than in control group (3 hours vs. 2 hours; P < 0.05).
