Table 2.
Tie and Ang expression and risk categories for GISTs (30 cases) n (%)
|
Ang-1 |
Ang-2 |
Ang-4 |
Tie-1 |
Tie-2 |
|||||||
| n | - | + | - | + | - | + | - | + | - | + | |
| GIST | 30 | 10 (33.3) | 20 (66.7) | 5 (16.7) | 25 (83.3) | 19 (63.3) | 11 (36.7) | 12 (40.0) | 18 (60.0) | 27 (90.0) | 3 (10.0) |
| Risk categories | NS | NS | NS | NS | NS | ||||||
| High | 6 | 1 (16.7) | 5 (83.3) | 2 (33.3) | 4 (66.7) | 6 (100) | 0 (0.0) | 1 (16.7) | 5 (83.3) | 5 (83.3) | 1 (16.7) |
| Intermediate | 4 | 2 (50.0) | 2 (50.0) | 1 (25.0) | 3 (75.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 2 (50.0) | 4 (100) | 0 (0.0) |
| Low | 15 | 6 (40.0) | 9 (60.0) | 2 (13.3) | 13 (86.7) | 8 (53.3) | 7 (46.7) | 5 (33.3) | 10 (66.7) | 13 (86.7) | 2 (13.3) |
| Very low | 5 | 1 (20.0) | 4 (80.0) | 0 (0.0) | 5 (100) | 3 (60.0) | 2 (40.0) | 4 (80.0) | 1 (20.0) | 5 (100) | 0 (0.0) |
| Mitosis counts (per 50 fields, HPF) | NS | NS | NS | NS | NS | ||||||
| < 2 | 19 | 7 (36.8) | 12 (63.2) | 3 (15.8) | 16 (84.2) | 11 (57.9) | 8 (42.1) | 9 (47.4) | 10 (52.6) | 17 (89.5) | 2 (10.5) |
| 2-5 | 7 | 2 (28.6) | 5 (71.4) | 1 (14.3) | 6 (85.7) | 4 (57.1) | 3 (42.9) | 2 (28.6) | 5 (71.4) | 6 (85.7) | 1 (14.3) |
| 6-10 | 2 | 1 (50.0) | 1 (50.0) | 1 (50.0) | 1 (50.0) | 2 (100) | 0 (0.0) | 0 (0.0) | 2 (100) | 2 (100) | 0 (0.0) |
| 10 < | 2 | 0 (0.0) | 2 (100) | 0 (0.0) | 2 (100) | 2 (100) | 0 (0.0) | 1 (50.0) | 1 (50.0) | 2 (100) | 0 (0.0) |
| Tumor size (cm in length) | NS | NS | NS | NS | NS | ||||||
| < 2 | 4 | 1 (25.0) | 3 (75.0) | 0 (0.0) | 4 (100) | 3 (75.0) | 1 (25.0) | 3 (75.0) | 1 (25.0) | 4 (100) | 0 (0.0) |
| 2-5 | 16 | 6 (37.5) | 10 (62.5) | 2 (12.5) | 14 (87.5) | 9 (56.3) | 7 (43.8) | 6 (37.5) | 10 (62.5) | 15 (93.8) | 1 (6.3) |
| 5-10 | 7 | 3 (42.9) | 4 (57.1) | 2 (28.6) | 5 (71.4) | 4 (57.1) | 3 (42.9) | 2 (28.6) | 5 (71.4) | 6 (85.7) | 1 (14.3) |
| > 10 | 3 | 0 (0.0) | 3 (100) | 1 (33.3) | 2 (66.7) | 3 (100) | 0 (0.0) | 1 (33.3) | 2 (66.7) | 2 (66.7) | 1 (33.3) |
NS: not significant.