Figure 6.

P63 ablation-induced cell invasion is largely mediated by CD82. (a and b) FaDu and MCF-10A cells were infected with lentivirus expressing shRNA against pan-p63 (shp63) or a control shRNA (shC). (a) Cells were subjected to transwell cell invasion assays, as described previously. Results are presented as mean and S.E. from three independent experiments. (b) Cells were subjected to cell proliferation analysis by counting the number of cells every 24 h with a hemacytometer. Results are presented as means and S.E. from three independent experiments. (c and d) FaDu and MCF-10A cells expressing shp63 or shC were infected with retrovirus expressing CD82 or a vector control (Vec). Puromycin-resistant cells were subjected to western blotting (c), or transwell cell invasion assays (d), as described previously. Results from cell invasion assays were quantitated and presented as mean and S.E. from three independent experiments. **P<0.01