Table 1.
Clinicopathologic characteristics of colorectal cancer with expression of COX-2
| Variable | n | COX-2 Positive n(%) | COX-2 Negative n(%) |
| Sex | |||
| Male | 73 | 50(68.5) | 23(31.5) |
| Female | 55 | 37(67.3) | 18(32.7) |
| Age(y) | 54 ± 12 | 56 ± 15 | |
| Histological differentiation | |||
| Well | 26 | 17(65.4) | 9 (34.6) |
| Moderate | 57 | 40(70.2) | 17(29.8) |
| Poor | 45 | 30(66.7) | 15(33.3) |
| Depth of invasion | |||
| T1-T2 | 81 | 48(59.3) | 33(40.7) |
| T3-T4 | 47 | 39(83.0) | 8 (17.0)a |
| Metastasis | |||
| Present | 50 | 42(84.0) | 8 (16.0) |
| Absent | 78 | 45(57.7) | 33(42.3)a |
| Duke's stage | |||
| A | 37 | 15(40.5) | 22(59.5) |
| B | 41 | 28(68.3) | 13(31.7) |
| C+D | 50 | 44(88.0) | 6 (12.0)a |
| VEGF expression | |||
| Positive | 49 | 40(81.6) | 9 (18.4) |
| Negative | 79 | 47(59.5) | 32(40.5)a |
| MVD (¯x± s) | 56 ± 16 | 43 ± 12a |
a
P < 0.05, vs positive.