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Effect of TRAIL on SW480 cells. SW480 cells were treated with TRAIL at the concentrations of 0, 10, 100, 500 and 1000 μg•l-1 for 24 h. Cell growth inhibition was assessed by MTT assay and confirmed by flow cytometry assay. Compared with TRAIL-sensitive leukaemic cell line Jurkat (IC50 0.42 μg•l-1), SW480 cells (IC50 > 1000 μg•l-1) were not responsive to TRAIL at concentration more than 100 times those active on Jurkat.
