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. 2003 Jun 15;9(6):1241–1245. doi: 10.3748/wjg.v9.i6.1241

Figure 2.

Figure 2

Effect of TRAIL and doxorubicin on SW480 cells. SW480 cells were treated with doxorubicin alone or a combination of doxorubicin with TRAIL at different concentrations. The combination resulted in the reduction of doxorubicin IC50 in cells (P < 0.05). Doxorubicin IC50 was 65.25 ± 3.48 when cells were treated by doxorubicin alone, while it was further reduced with the increased concentrations of TRAIL. Doxorubicin IC50 was 43.17 ± 2.54 μmol•l-1 when it was combined with 10 mg•l-1of TRAIL, 0.51 ± 0.02 μmol•l-1IC50 when combined with 100 μg•l-1 TRAIL, and 0.44 ± 0.02 μmol•l-1 IC50 when combined with 1000 μg•l-1TRAIL.