Table 1.
Parameters | Pre treatment | Post treatment | Chronic gastritis |
N of patients | 56 | 16 | |
Age (mean ± SD) | 60.13 ± 17.38 | 57.11 ± 15.81 | |
Male/Female | 46/10 | 8/8 | |
Non smoking/smoking | 16/40 | 6/10 | |
Gastric ulcer | 21 | 0 | - |
Duodenal ulcer | 35 | 0 | - |
History of NSAID use | 33/52 | 4/16 | |
H pylori positive/negative | 41/11a | 7/45b | 11/5 |
Patients with evidence of gastritis | 49/52a | 34/52d | 13/16 |
(Total updated Sydney Score > 0) | |||
Site of gastric inflammation | |||
Antrum (no of patients) | 28 | 21 | 8 |
Corpus (no of patients) | 8 | 6 | 3 |
Disseminated (no of patients) | 13 | 7 | 5 |
Total updated Sydney score (mean ± SD) | 4.69 ± 1.93a | 2.69 ± 1.22f | 4.27 ± 0.65 |
Neutrophil infiltration score (mean ± SD) | 1.77 ± 0.59a | 0.81 ± 0.32f | 1.73 ± 0.73 |
Monocyte infiltration score (mean ± SD) | 2.15 ± 0.68a | 1.05 ± 0.61f | 1.73 ± 0.38 |
Lymphocyte infiltration score (mean ± SD) | 0.87 ± 0.35a | 0.13 ± 0.08c | 0.69 ± 0.32 |
Mucosal atrophy score (mean ± SD) | 0.55 ± 0.17a | 0.38 ± 0.11e | 0.58 ± 0.30 |
Intestinal metaplasia (mean ± SD) | 0.29 ± 0.04a | 0.13 ± 0.08e | 0.19 ± 0.07 |
Density of H pylori (mean ± SD) | 1.56 ± 0.28a | 0.33 ± 0.07f | 1.45 ± 0.39 |
P vs chronic gastritis, non significant; b,d,fP < 0.01,
P < 0.05, vs pre-treatment scores.
P vs pre-treatment scores; non significant.