Table 2.
Concentrations of soluble triggering receptor expressed on myeloid cells-s (sTREM-1) and tumor necrosis factor-alpha (TNFα) of supernatants of tissue samples taken from patients with either duodenal or gastric ulcer disease or chronic gastritis at pre-treatment
| Parameters |
Duodenal ulcer |
Gastric ulcer |
Chronic Gastritis |
|||
| H pylori (+) | H pylori (-) | H pylori (+) | H pylori (-) | H pylori (+) | H pylori (-) | |
| N | 35 | 0 | 14 | 7 | 9 | 7 |
| sTREM-1 [median (range), pg/g of tissue] | ||||||
| 0 | 32.41 (13.32) | - | 317.27 (73.98)a | 112.41 (38.71) | 6.21 (0.81)c | 5.18 (0.77) |
| LPS | 102.41 (40.43) | - | 455.41 (98.53)b | 214.55 (44.81) | 12.67 (2.16)c | 9.37 (1.55) |
| Gastric juice | 17.91 (7.11) | - | 150.14 (41.16)c | 118.48 (54.93) | 10.07 (2.02)c | 7.42 (1.22) |
| TNFα [median (range), pg/g of tissue] | ||||||
| 0 | 10.62 (2.07) | - | 7.58 (1.75)c | 6.40 (1.52) | 8.11 (1.31)c | 5.98 (1.45) |
| LPS | 28.25 (3.35) | - | 45.33 (13.06)c | 21.44 (8.12) | 19.07 (4.72)c | 17.87 (2.11) |
| Gastric juice | 18.02 (5.97) | - | 10.76 (2.08)c | 8.51 (2.05) | 10.17 (3.23)c | 9.13 (1.61) |
Patients were divided as either H pylori-positive or H pylori-negative. LPS: Endotoxin of Escherichia coli O144:H4.
a
P < 0.05,
b
P < 0.01, vs H pylori negative patients.
c
P vs H pylori negative patients. non-significant.