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. 2015 Oct 20;6:222. doi: 10.3389/fneur.2015.00222

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Copyright © 2015 Turner, Lucke-Wold, Logsdon, Robson, Dashnaw, Huang, Smith, Huber, Rosen and Petraglia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Track plots acquired across spatial acquisition and probe testing in rats. (A–D) Track plots generated from anesthetized control animals on days 21, 23, 26, and during the probe test. (E–H) Track plots generated from single-injured animals on days 21, 23, 26, and during the probe test post-injury. (I–L) Track plots generated from repetitively injured animals on days 21, 23, 26, and during the probe test post-injury. Injured animals appear to spend more time exhibiting thigmotaxis behaviors (circling edge of pool) on later days and in the probe trial fail to spend as much time as the anesthetized control animals within the probe region and the direct area surrounding the probe region.