Table 1.

Histomorphometry of WT, Ebi2^−/−, and Ch25h^−/− mice

Strain	n	BV/TV	Tb.N	Tb.Th	Tb.Sp	OCS/BS	NOC/TAR	NOC/BPm	OBS/BS	OBS/OS	NOB/TAR	NOB/BPm	NOB/Opm
		%	mm−1	µm	µm	%			%	%
WT	8	19.80 ± 7.75	4.69 ± 0.99	41.20 ± 7.55	179.65 ± 45.65	9.59 ± 5.22	80.62 ± 22.67	4.28 ± 1.32	30.59 ± 7.55	11.74 ± 4.66	105.60 ± 40.20	11.41 ± 4.51	36.68 ± 7.14
Ebi2−/−	4	31.34 ± 11.01a	5.56 ± 0.95	55.09 ± 13.51a	131.04 ± 51.20a	8.85 ± 4.12	59.90 ± 22.48a	3.78 ± 1.15	32.37 ± 6.17	12.99 ± 4.72	131.36 ± 57.42	11.64 ± 4.45	36.01 ± 12.16
Ch25h−/−	10	23.57 ± 11.74a	5.10 ± 1.17	44.50 ± 11.63	160.77 ± 53.42	6.17 ± 1.86b	55.20 ± 11.28a	4.21 ± 1.19	47.11 ± 9.46	14.54 ± 5.85	141.59 ± 83.40	13.20 ± 5.27	37.61 ± 7.19

Data are presented as mean ± SD. BV/TV, bone volume per total volume; Tb.N, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; OCS/BS, OC surface; NOC/TAR, OC number per total area; NOC/BPm, OC number per bone perimeter; OBS/BS, OB surface per bone surface; OB/OS, OB surface/osteoid surface; NOB/TAR, OB number per total area; NOB/BPm, OB number per bone perimeter; NOB/Opm, OB number per osteoid perimeter.

^aSignificant difference from WT controls, P < 0.05.

^bP = 0.06.