Table 2.
Cell line | Tumorigenicity | Androgen sensitivity | AR | PTEN | p53 |
---|---|---|---|---|---|
RWPE-1 | N/A | Sensitive | + | WT | WT |
LNCaP | Very low | Sensitive | + | Mutant | WT |
C4-2 | Moderate | Insensitive | + | Mutant | WT |
PC3 | High | Insensitive | − | Null | Null |
22Rv-1 | Low | Sensitive | Variants | WT | Mutant |