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. 2015 Oct 19;16:230. doi: 10.1186/s13059-015-0788-9

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© Marques et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Origin usage is not equivalent in Leishmania and T. brucei. Synteny conservation is shown between T. brucei (Tbr) chromosome 8 and L. major (Lmj) chromosomes 7, 10 and 23, and between L. major (Lmj) chromosome 31 and T. brucei (Tbr) chromosomes 4 and 8, comparing the relative strength of the replication origins found within these chromosomes. S/G2 DNA sequence depth ratios and coding sequence organisation are as detailed in Fig. 1. Synteny blocks are boxed and their relative orientation indicated; the approximate location of the origins is shown by vertical lines. Double-headed arrows denote local rearrangements