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. 2015 Oct 19;16:230. doi: 10.1186/s13059-015-0788-9

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© Marques et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Origins are found at specific genomic loci in Leishmania but not in T. brucei. Scatter plot analysis of the length of strand switch regions (SSRs) in L. major, L. mexicana and T. brucei, comparing SSRs that have been mapped as showing origin activity (circles) with those in which origin activity has not been detected (squares). Horizontal lines show the mean, and vertical lines standard error of the mean; ***P < 0.0001, a significant difference in SSR size between the two groups; ns denotes that no significant size difference was seen. Origin-active SSRs in L. major chromosomes 29 and 36 are highlighted in black, as are the syntenic SSRs in L. mexicana chromosomes 8 and 20, which are not origin-active (further detail in Figure S9 in Additional file 1)