Figure 4.
Docetaxel clearance as a function of the most common variant haplotypes in (a) SLCO1B3 (haplotype GAAGAT at positions 334, 439, 699, 767, 1559, and 1679; SLCO1B3*1), (b) ABCB1 (haplotype CGC at positions 1236, 2677, and 3435; ABCB1*1), and (c) ABCC2 (haplotype ACGTCG at positions −1019, −24, 1249, IVS26 −34, 3972, and 4544; ABCC2*1). Each symbol represents an individual patient, and horizontal lines indicate median values.