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. Author manuscript; available in PMC: 2015 Oct 21.
Published in final edited form as: Clin Pharmacol Ther. 2008 May 28;85(2):155–163. doi: 10.1038/clpt.2008.95

Figure 5.

Figure 5

Visual genotypes of the CYP3A locus in CEPH-HapMap samples stratified on the basis of informative CYP3A genotypes. Each sample (identified on the x-axis) is arranged by CYP3A locus SNPs (on the y-axis). Genotypes are color-coded as follows: gray, homozygous wild type; orange, heterozygous; red, homozygous variant. Groups labeled 1 and 2 represent CYP3A5 expressors carrying CYP3A5*1A (rs776746) stratified by the presence or absence of the CYP3A4*1B (rs2740574) allele, respectively. Among CYP3A5 non-expressors, groups labeled 3, 4, 5, and 6 were further segregated by CYP3A7 SNPs, the SNP 3′ of CYP3A4 (rs1233983), and the CYP3A4 intron 7 SNP (rs2246709), respectively.

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