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. 2014 Oct 30;13(23):3645–3658. doi: 10.4161/15384101.2014.964108

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© 2014 The Author(s). Published with license by Taylor & Francis Group, LLC

© Emma Lindgren, Sara Hägg, Fosco Giordano, Johan Björkegren, and Lena Ström

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 6. — Cohesin binding genome wide and at the Chr. VI DSB. (A and B) Chromosomal association of Flag-tagged Scc1 analyzed by ChIP sequencing in WT and scc2–4 cells in the presence and absence of DSB induction at Chr. VI as indicated. Orange peaks display significant chromosomal binding sites where the x-axes show chromosomal positions and the y-axes show linear fold enrichment. (A) Shown is a representative undamaged region of Chr. III. (B) Shown is the region immediately surrounding the DSB on Chr. VI. Gray arrow points at the HO break site.