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. 2015 Aug 15;8(8):11905–11912.

Table 1.

Characteristics of studies included in the meta-analysis

Reference Source of controls Area Ethnicity Case no. Control no. Case Control HWE



TT CT CC TT CT CC X2 P
Hu 1999 [12] PB+HB Guangdong Han 59 132 22 22 15 34 76 22 3.43 0.064
Persson 1999 [13] PB Beijing Not stated 76 90 33 34 9 36 44 10 0.40 0.526
Song 1999 [14] PB Beijing Not stated 150 391 35 93 22 162 173 56 0.79 0.375
Song 2001 [15] PB Beijing Not stated 217 404 60 129 28 173 175 56 1.19 0.275
Yin 2001 [16] HB Jiangsu Not stated 84 84 36 35 13 28 38 18 0.57 0.451
Zhou 2002 [17] HB Hubei Not stated 92 98 34 43 15 51 34 13 3.29 0.070
Wang 2003 [18] PB Beijing + Tianjin Han 162 181 64 76 22 65 78 38 2.54 0.111
Dong 2004 [19] HB Sichuan Not stated 82 91 35 36 11 46 35 10 0.71 0.401
Liang 2004 [20] HB Jiangsu Han 152 152 50 82 20 70 71 11 1.52 0.218
Li 2004 [21] HB Beijing Not stated 217 200 93 88 36 85 89 26 0.13 0.722
Li 2005 [22] PB Henan Han 103 138 27 64 12 73 54 11 0.05 0.819
Ng 2005 [23] HB Singapore Not stated 124 162 22 61 41 19 87 56 2.87 0.090
Qian 2006 [24] PB Tianjin Han 108 108 45 33 30 44 52 12 0.33 0.563
Tao 2007 [25] Not stated Anhui Not stated 47 94 24 19 4 43 37 14 1.59 0.208
Xia 2008 [26] HB Gansu Han 58 116 17 36 5 40 58 18 0.16 0.688
Zhu 2010 [27] PB Hunan Not stated 160 160 55 68 37 68 66 26 2.08 0.149
Tuerxun 2011 [28] PB Xinjiang Han 59 84 19 27 13 33 45 6 3.19 0.074
Wang 2012 [29] PB Henan Han 209 256 61 106 42 87 120 49 0.44 0.508
Li 2012 [30] PB Beijing Not stated 217 198 93 88 36 83 89 26 0.08 0.781
Huang 2013 [31] PB Hunan Han 168 201 51 83 34 61 93 47 0.99 0.320
Jiang 2014 [32] PB Inner Mongolia Mongolian 142 190 28 59 55 64 95 31 0.18 0.668
Jiang 2014 [32] PB Inner Mongolia Han 180 266 37 71 72 87 126 53 0.36 0.547
Yang 2014 [33] PB Hebei Not stated 150 136 60 64 26 62 56 18 0.87 0.350

PB: Population-based, HB: hospital-based.