Table 3.

Meta-Analysis of PPARG rs1801282 C>G polymorphism with the breast cancer risk

	No. of study	G vs. C			GG vs. CC			GG+CG vs. CC			GG vs. CG+CC			CG vs. CC
		OR (95% CI)	P	P (Q-test)	OR (95% CI)	P	P (Q-test)	OR (95% CI)	P	P (Q-test)	OR (95% CI)	P	P (Q-test)	OR (95% CI)	P	P (Q-test)
Total	8	0.95 (0.81-1.11)	0.503	0.065	1.02 (0.54-1.93)	0.963	0.062	0.92 (0.82-1.03)	0.132	0.119	1.05 (0.56-1.96)	0.884	0.071	0.91 (0.81-1.02)	0.107	0.178
Ethnicity
Asians	2	1.19 (0.86-1.64)	0.302	0.225	2.00 (0.18-22.09)	0.573	NA	1.18 (0.85-1.65)	0.327	0.192	2.00 (0.18-22.18)	0.571	NA	1.17 (0.83-1.64)	0.363	0.171
Caucasians	4	0.85 (0.75-0.97)	0.016	0.158	0.90 (0.37-2.16)	0.809	0.038	0.83 (0.71-0.96)	0.011	0.287	0.94 (0.39-2.25)	0.890	0.038	0.82 (0.71-0.96)	0.011	0.353
Mixed populations	2	1.05 (0.86-1.26)	0.647	0.265	1.39 (0.66-2.92)	0.389	0.184	1.03 (0.83-1.27)	0.792	0.402	1.38 (0.66-2.90)	0.394	0.190	1.01 (0.81-1.25)	0.939	0.582
Menopausal status
Post-menopaused	3	0.85 (0.63-1.15)	0.298	0.075	1.21 (0.41-3.57)	0.723	0.062	0.79 (0.67-0.95)	0.011	0.202	1.29 (0.46-3.64)	0.631	0.074	0.77 (0.64-0.92)	0.005	0.442
Mixed status	5	1.00 (0.88-1.15)	0.958	0.237	0.85 (0.30-2.38)	0.750	0.093	1.01 (0.87-1.01)	0.865	0.395	0.85 (0.31-2.35)	0.754	0.099	1.02 (0.88-1.18)	0.801	0.537
Source of controls
PB	6	0.91 (0.77-1.06)	0.234	0.093	0.97 (0.49-1.93)	0.930	0.039	0.89 (0.79-1.00)	0.051	0.203	1.00 (0.51-1.98)	0.991	0.045	0.88 (0.78-0.99)	0.041	0.322
HB	2	1.19 (0.86-1.64)	0.302	0.225	2.00 (0.18-22.09)	0.573	NA	1.18 (0.85-1.65)	0.327	0.192	2.00 (0.18-22.09)	0.571	NA	1.17 (0.83-1.64)	0.363	0.171
Sample sizes
< 1000	5	1.02 (0.85-1.22)	0.829	0.242	1.78 (0.85-3.73)	0.125	0.316	0.98 (0.81-1.19)	0.837	0.252	1.86 (0.89-3.89)	0.102	0.332	0.94 (0.77-1.15)	0.563	0.231
≥ 1000	3	0.90 (0.72-1.12)	0.341	0.043	0.80 (0.37-1.73)	0.578	0.064	0.89 (0.71-1.12)	0.318	0.069	0.83 (0.39-1.74)	0.619	0.075	0.89 (0.77-1.03)	0.118	0.115

PB: Population-based; HB: Hospital-based.