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. 2015 Aug 15;8(8):12685–12695.

Table 6.

Summary of results of the meta-analysis from different comparative genetic models in the subgroup analysis

No. (cases/controls) G vs. A GG vs. AA GG+AG vs. AA GG vs. AG+AA




OR (95% CI) P P (Q-test) OR (95% CI) P P (Q-test) OR (95% CI) P P (Q-test) OR (95% CI) P P (Q-test)
Total 2080/2833 0.87 (0.71-1.08) 0.205 0.000 0.73 (0.47-1.14) 0.173 0.000 0.88 (0.69-1.12) 0.296 0.007 0.79 (0.54-1.16) 0.232 0.000
Ethnicity
    Asians 1221/1365 0.81 (0.62-1.07) 0.133 0.001 0.60 (0.31-1.15) 0.123 0.000 0.87 (0.73-1.04) 0.119 0.370 0.61 (0.32-1.18) 0.143 0.000
    Caucasians 859/1468 0.96 (0.66-1.39) 0.817 0.001 0.93 (0.46-1.88) 0.832 0.003 0.85 (0.48-1.52) 0.592 0.002 1.08 (0.72-1.63) 0.694 0.060
Sample sizes
    < 600 581/684 0.71 (0.47-1.06) 0.097 0.000 0.45 (0.18-1.13) 0.089 0.000 0.71 (0.42-1.18) 0.183 0.003 0.53 (0.24-1.13) 0.100 0.000
    ≥ 600 1499/2149 1.07 (0.85-1.34) 0.548 0.030 1.16 (0.74-1.81) 0.528 0.032 0.97 (0.81-1.15) 0.711 0.178 1.18 (0.83-1.68) 0.361 0.053
Publication year
    > 2009 895/937 0.66 (0.46-0.96) 0.030 0.006 0.43 (0.19-0.95) 0.037 0.005 0.62 (0.38-1.01) 0.055 0.045 0.53 (0.25-1.13) 0.100 0.001
    ≤ 2009 1185/1896 1.06 (0.88-1.29) 0.543 0.037 1.09 (0.70-1.69) 0.696 0.017 1.10 (0.94-1.30) 0.223 0.457 1.07 (0.72-1.59) 0.754 0.010