Table 6.
No. (cases/controls) | G vs. A | GG vs. AA | GG+AG vs. AA | GG vs. AG+AA | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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OR (95% CI) | P | P (Q-test) | OR (95% CI) | P | P (Q-test) | OR (95% CI) | P | P (Q-test) | OR (95% CI) | P | P (Q-test) | ||
Total | 2080/2833 | 0.87 (0.71-1.08) | 0.205 | 0.000 | 0.73 (0.47-1.14) | 0.173 | 0.000 | 0.88 (0.69-1.12) | 0.296 | 0.007 | 0.79 (0.54-1.16) | 0.232 | 0.000 |
Ethnicity | |||||||||||||
Asians | 1221/1365 | 0.81 (0.62-1.07) | 0.133 | 0.001 | 0.60 (0.31-1.15) | 0.123 | 0.000 | 0.87 (0.73-1.04) | 0.119 | 0.370 | 0.61 (0.32-1.18) | 0.143 | 0.000 |
Caucasians | 859/1468 | 0.96 (0.66-1.39) | 0.817 | 0.001 | 0.93 (0.46-1.88) | 0.832 | 0.003 | 0.85 (0.48-1.52) | 0.592 | 0.002 | 1.08 (0.72-1.63) | 0.694 | 0.060 |
Sample sizes | |||||||||||||
< 600 | 581/684 | 0.71 (0.47-1.06) | 0.097 | 0.000 | 0.45 (0.18-1.13) | 0.089 | 0.000 | 0.71 (0.42-1.18) | 0.183 | 0.003 | 0.53 (0.24-1.13) | 0.100 | 0.000 |
≥ 600 | 1499/2149 | 1.07 (0.85-1.34) | 0.548 | 0.030 | 1.16 (0.74-1.81) | 0.528 | 0.032 | 0.97 (0.81-1.15) | 0.711 | 0.178 | 1.18 (0.83-1.68) | 0.361 | 0.053 |
Publication year | |||||||||||||
> 2009 | 895/937 | 0.66 (0.46-0.96) | 0.030 | 0.006 | 0.43 (0.19-0.95) | 0.037 | 0.005 | 0.62 (0.38-1.01) | 0.055 | 0.045 | 0.53 (0.25-1.13) | 0.100 | 0.001 |
≤ 2009 | 1185/1896 | 1.06 (0.88-1.29) | 0.543 | 0.037 | 1.09 (0.70-1.69) | 0.696 | 0.017 | 1.10 (0.94-1.30) | 0.223 | 0.457 | 1.07 (0.72-1.59) | 0.754 | 0.010 |