Table 3.
Rate of anastomotic leakage in patients with or without diverting stoma in LAR studies
| Author | Year | Study Design | Patients (n) | Anastomotic Leakage | AL Requiring Laparotomy | ||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
||||||||
| DS (%) | Non-DS (%) | P | DS (%) | Non-DS (%) | P | ||||
| Law WI | 2000 | Prospective | 196 | 5 (4.85%) | 15 (16.13%) | .009 | 0 (0%) | 10 (10.75%) | < .001 |
| Nesbakken A | 2001 | - | 92 | 5 (17.24%) | 12 (19.05%) | .835 | 1 (3.45%) | 11 (17.46%) | .063 |
| Z’graggen K | 2001 | - | 41 | 3 (7.32%) | - | 1 (2.44%) | - | ||
| Ho YH | 2002 | - | 88 | 7 (7.95%) | - | 1 (1.14%) | - | ||
| Leester B | 2002 | Retrospective | 249 | 7 (9.46%) | 9 (5.14%) | .204 | 0 (0%) | 8 (4.57%) | .061 |
| Marusch F | 2002 | Prospective | 482 | 16 (10.81%) | 35 (10.48%) | .913 | 3 (2.03%) | 23 (6.89%) | .029 |
| Kanellos I | 2002 | - | 82 | - | 8 (9.76%) | - | 4 (4.88%) | ||
| Eckmann C | 2004 | - | 306 | - | 30 (9.80%) | - | 12 (3.92%) | ||
| Vorobiev GI | 2004 | - | 27 | 2 (7.41%) | - | 0 (0%) | - | ||
| Chamlou R | 2007 | - | 90 | 8 (8.89%) | - | 3 (3.33%) | - | ||
| Chude GG | 2008 | RCT | 256 | 3 (2.21%) | 12 (10.00%) | .008 | 0 (0%) | 4 (3.33%) | .031 |
| Lefebure B | 2008 | Retrospective | 132 | 3 (7.14%) | 10 (11.11%) | .476 | 0 (0%) | 5 (5.56%) | .119 |
| Ulrich AB | 2009 | RCT | 34 | 1 (5.56%) | 6 (37.50%) | .021 | 0 (0%) | 6 (37.50%) | .004 |
| Peng J | 2010 | - | 639 | - | 45 (7.04%) | - | 12 (1.88%) | ||
| Akasu T | 2010 | Retrospective | 120 | 14 (13.21%) | 1 (7.14%) | .519 | 6 (5.66%) | 0 (0%) | .361 |
| Kruschewski M | 2011 | - | 128 | 15 (11.72%) | - | 12 (9.38%) | - | ||
| Shiomi A | 2011 | Retrospective | 329 | 9 (7.50%) | 24 (11.48%) | .246 | 1 (0.83%) | 13 (6.22%) | .019 |
| Fouda E | 2011 | - | 56 | 1 (5.88%) | 7 (17.95%) | .235 | 0 (0%) | 7 (17.95%) | .061 |
| Glancy DG | 2012 | - | 144 | 5 (8.93%) | 8 (9.09%) | .973 | 5 (8.93%) | 5 (5.68%) | .454 |
| Biondo S | 2012 | - | 106 | 2 (1.89%) | - | 1 (0.94%) | - | ||
| Rondelli F | 2012 | - | 143 | 5 (3.50%) | - | 4 (2.80%) | - | ||
| Gong H | 2012 | Retrospective | 62 | 5 (19.23%) | 0 (0%) | .006 | 2 (7.69%) | 0 (0%) | .090 |
| Total | 3,802 | 116 (7.74%) | 222 (9.64%) | .045 | 40 (2.67%) | 120 (5.21%) | < .001 | ||
AL, anastomotic leakage; DS, diverting stoma; RCT, randomized controlled trial.