Table 1.
Univariate analysis of patients with myasthenia gravis with and without prolonged postoperative extubation
| Variables | Group I (n = 14) | Group II (n = 47) | P value | OR | 95% CI |
|---|---|---|---|---|---|
| Gender (n) | 0.795 | 1.173 | 0.352-3.910 | ||
| Male | 6 | 22 | |||
| Female | 8 | 25 | |||
| Age (years) | 40.3 + 11.0 | 33.8 + 15.8 | 0.160 | 1.030 | 0.988-1.075 |
| MGFA clinical classification | 0.015* | 1.581 | 0.966-2.587 | ||
| I | 3 | 30 | |||
| IIa + IIb | 10 | 14 | |||
| IIIa + IIIb + IV | 1 | 3 | |||
| QMG grade | 9.64 + 2.79 | 4.02 + 4.11 | 0.000* | 1.368 | 1.149-1.628 |
| Muscle strength | 0.000* | 0.279 | 0.131-0.593 | ||
| Level 2 | 1 | 2 | |||
| Level 3 | 8 | 3 | |||
| Level 4 | 3 | 12 | |||
| Level 5 | 2 | 30 | |||
| Prednisone (mg) | 13.2 + 13.1 | 5.3 + 10.5 | 0.023* | 1.059 | 1.008-1.112 |
| Pyridostigmine (mg) | 175.7 + 36.9 | 110.4 + 93.6 | 0.000* | 1.011 | 1.001-1.020 |
| Smoking history | 0.650 | 1.324 | 0.393-4.457 | ||
| With | 6 | 17 | |||
| Without | 8 | 30 | |||
| History of chronic lung diseases | 0.549 | 2.291 | 0.473-11.098 | ||
| With | 3 | 5 | |||
| Without | 11 | 42 | |||
| History of chronic cardiovascular diseases | 0.440 | 2.286 | 0.558-9.366 | ||
| With | 4 | 7 | |||
| Without | 10 | 40 | |||
| Lung function | 0.031* | 4.875 | 1.336-17.793 | ||
| Normal | 7 | 39 | |||
| Abnormal | 7 | 8 | |||
| ALT (U/L) | 33.4 + 19.2 | 28.9 + 20.7 | 0.470 | 1.010 | 0.983-1.039 |
| ALB (g/L) | 45.0 + 9.9 | 44.4 + 4.2 | 0.814 | 1.018 | 0.923-1.123 |
| Cr (μmol/L) | 64.4 + 28.3 | 63.6 + 20.0 | 0.916 | 1.011 | 0.974-1.029 |
| CHE (mmol/L) | 3235.2 + 832.0 | 3959.6 + 936.0 | 0.012* | 0.999 | 0.998-1.000 |
| K+ (mmol/L) | 4.23 + 0.26 | 4.19 + 0.36 | 0.677 | 1.477 | 0.244-8.960 |
| Hb (g/L) | 125.7 + 14.9 | 127.0 + 14.7 | 0.772 | 0.994 | 0.953-1.036 |
| AchR antibody | 0.000* | 14.143 | 2.793-71.625 | ||
| (+) | 12 | 14 | |||
| (-) | 2 | 33 | |||
| Impaired swallow muscle activity | 0.004* | 7.619 | 2.018-28.768 | ||
| With | 8 | 7 | |||
| Without | 6 | 40 |
*
P < 0.05, group I vs. group II.
Abbreviations: OR, odds ratio; CI, confidence interval; MGFA, Myasthenia Gravis Foundation of America; QMG, quantitative myasthenia gravis; ALT, alanine transferase, ALB, albumin, Cr, creatinine; CHE, cholinesterase; Hb, hemoglobin; AchR, acetylcholine receptor.