Table 4.
Effect of subchronic administration of “Huhezi” on serum biochemistry parameters
| Group | High dose 1000 mg/kg | Middle dose 500 mg/kg | Low dose 250 mg/kg | Saline control |
|---|---|---|---|---|
| ALB (g/L) | 30.53±2.43 | 31.10±1.99 | 26.68±9.48 | 30.53±2.20 |
| ALP (U/L) | 227.00±59.85 | 202.33±79.56 | 214.00±68.96 | 199.83±21.01 |
| ALT (U/L) | 34.67±4.08* | 36.17±12.97* | 37.00±3.74* | 25.17±6.62 |
| AST (U/L) | 126.00±16.64 | 114.67±22.61 | 126.67±12.85 | 134.67±13.81 |
| BUN (mmol/L) | 5.29±1.44 | 5.92±0.68 | 3.83±1.47 | 4.74±0.77 |
| Ca (mmol/L) | 2.30±0.20 | 2.27±0.26 | 7.12±7.92* | 2.24±0.10 |
| CHO (mmol/L) | 2.07±0.27 | 2.04±0.47 | 3.77±1.65* | 2.02±0.36 |
| CRE (umol/L) | 48.50±8.64 | 48.50±3.99 | 53.17±26.29 | 44.50±4.93 |
| GLU (mmol/L) | 5.54±1.25 | 6.22±0.81 | 6.86±2.09 | 5.32±0.96 |
| P (mmol/L) | 2.29±0.18 | 2.39±0.21 | 1.63±0.56* | 2.15±0.10 |
| TBIL (umol/L) | 4.83±0.69 | 4.49±1.60 | 6.51±2.33 | 7.78±4.70 |
| TP (g/L) | 62.12±5.63 | 62.35±4.81 | 63.48±5.71 | 60.47±3.27 |
Notice: The statistical significance is indicated with “*” in the column “high dose”, “middle dose” and “low dose” when comparing data of dose group with the saline group
*
means significant difference. P<0.05.