Table 1.
Characteristics of the studies included in the meta-analysis of intra-articular injection of HA versus placebo (saline solution)
| Author, year | Molecular weight of HA (kDa) | Number of injections/ number of cycles | Cross-linked | Industry funding |
|---|---|---|---|---|
| Shichikawa, 198325 | NA | 5/1 | No | Unclear |
| Puhl, 199326 | 900 | 5/1 | No | Yes |
| Altman, 200427 | 1000 | 1/1 | No | Yes |
| Petrella, 200629 | 600 | 3/1 | No | Yes |
| Lundsgaard, 200830 | 700 | 4/1 | No | Yes |
| Altman, 200928 | 3000 | 3/1 | No | Yes |
| Chevalier, 201032 | 6000 | 1/1 | Yes | Yes |
| Navarro-Sarabia, 201131 | 900 | 5/4 | No | Yes |
HA, hyaluronic acid; NA, not available.